Hunt for venture capital firms in Boston? You’ve landed in the right place. Fueled by elite institutions like MIT and Harvard, Boston—is a nexus of innovation, offering a wealth of resources, state-of-the-art infrastructure, and a highly skilled workforce. And in this city, progress is perpetual.

  • Boston’s 2024 investment is projected to soar to US$8 billion, up 25% from last year.
  • Early-stage Boston venture capital ventures dominate, with AI and biotech snagging 40% of VC interest.

Sorting through the flood of VCs can be overwhelming, so explore our curated list of top Boston VC firms tailored to your startup’s needs. Funding focus, investment activity, finances, and contact info—all at your fingertips.

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1. General Catalyst Partners

➡️ General Catalyst Partners, sailing strong for over 20 years and $5B+ in investments, this VC powerhouse supports innovators worldwide, fueling unicorns like Airbnb and Stripe. As catalyst advisors, they go beyond funding, offering mentorship, recruiting, scaling, M&A, and strategic guidance.

Industries: Consumer, Enterprise, FinTech&Crypto, Health Assurance

Funding stage: Early stage-Growth stage

Average check size: $500K-$2M

Number of investments: 400+

Number of exits: 60+

Notable portfolio companies: Circle, HubSpot, Vroom

Contacts: LinkedIn

2. Battery Ventures

➡️ Battery Ventures, a global venture leader for nearly 40 years, specializes in AI and cybersecurity. Their portfolio boasts 426 companies and 167 M&A deals, including success stories like Coinbase and Wayfair.

Industries: Tech-focused (application software, infrastructure software, consumer, and industrial tech+ life science tools)

Funding stage: All

Average check size: $1M-$100M+

Value-added beyond money: 

The company also offers focused expertise in recruiting and human resources, marketing/communications, business development, go-to-market, and growth and leadership (check it out here).

Number of investments: 800+

Number of exits: 190+

Contacts: LinkedIn, Contact page

3. Polaris Partners

➡️ Polaris Partners has rocked the investment scene since 1996 with $4.3 billion. They’ve backed over 400 investments, resulting in 100+ successful exits, mainly in healthcare and biotech companies. Beyond providing funds, they’re hands-on mentors for startups, helping them go from zero to hero in the VC world. 

Industries: Biotech and Healthcare

Funding stage: All

Average check size: $500K-$5M

Notable portfolio companies: Gossamer Bio, Syros, Ajax Health

Contacts: LinkedIn, Email 

4. OpenView

➡️ OpenView, since 2006, has invested in top-notch software companies, turning them into market leaders. With 100+ nurtured ventures, 30% find success. OpenView—isn’t just a VC; it’s a growth catalyst, sharing SaaS best practices and shaping success stories.

Industries: SaaS

Funding stage: Growth, Early stage, Late stage

Average check size: Undisclosed

Value-added beyond money: 

Expansion Platform—specialized support system that boosts software startups with targeted support in hiring, customer satisfaction, and expansion challenges. It ensures a smoother growth journey from early to later stages.

Number of investments: 60+

Number of exits: 30+

Contacts: Email, LinkedIn

5. Third Rock Ventures

➡️ Third Rock Ventures, Boston’s powerhouse VC. Over 80 companies were launched, $3.8B was raised, and a focus was on tackling health challenges like cancer. They empower startups with expert connections and knowledge sharing. Notable names in their portfolio are Celsius, Moma, and Ablexis.

Funding stage: Undisclosed

Average check size: Undisclosed

Number of investments: 60+

Number of exits: 30+

Contacts: Email, LinkedIn

6. Highland Capital Partners

➡️ Highland Capital Partners, a pioneering venture capital firm since 1987. With $7B in assets, 200+ exits, 50+ IPOs, and 40 unicorns, they supercharge startups in cybersecurity, fintech, and beyond. They’ve created hundreds of game-changing businesses worldwide, from Silicon Valley to Shanghai.

Industries: Consumer and Enterprise Technology (Cybersecurity, E-commerce, Education, and Media)

Funding stage: Early stage, Growth stage

Average check size: $5M-$200M

Number of investments: 600+

Number of exits: 200+

Notable portfolio companies: Rent the Runway, 2U, Catalant

Contacts: Email, LinkedIn

Related read:

7. .406 Ventures

➡️ .406 Ventures, the biggest early-stage tech kingmaker, among top venture capital firms in Boston. With 60+ investments, including standouts like Compass and Nomad. Recently, Indico Data snagged innovation awards, adding to why .406 Ventures is a VC rockstar!

Funding stage: Early stage

Average check size: $2M-$5M

Value-added beyond money: 

  • Student fellows program
  • Executive councils
  • Executives and entrepreneurs in residence

Number of exits: Undisclosed

Contacts: Email, LinkedIn

8. Advanced Technology Ventures

➡️ Advanced Technology Ventures is a bi-coastal venture capital firm making waves in communications, software, healthcare, and cleantech. They’re all about early and growth stages, turning promising companies into market leaders. With over $1.8 billion invested, ATV is shaping the future venture capital firm in Massachusetts and Boston.

Industries: IT, Healthcare, and Cleantech

Funding stage: Early stage, Growth stage

Average check size: $10M-$50M

Number of investments: 200+

Number of exits: 70+

Notable portfolio companies: Tripwire, Cedexis, Actifio

Contacts: Email, LinkedIn

9. Bain Capital Ventures

➡️ Bain Capital Ventures is one of the top VC firms in Boston that supports startups in tech. They’ve helped over 200 companies like DocuSign and LinkedIn. With $5.2 billion in assets, they offer more than money—providing strategic talent, connections, and support from start to IPO.

Industries: FinTech, Apps, Infra, Commerce

Funding stage: Early stage-Growth stage

Average check size: $1M-$100M

Value-added beyond money: 

The company offers expert guidance, Bain Capital connections for customers and partners, help with customer development, and targeted domain advice.

Number of investments: 400+

Number of exits: Undisclosed

Notable portfolio companies: Docusign, LinkedIn, Rapid7

Contacts: Email, LinkedIn

10. Charles River Ventures (CRV)

➡️ Charles River Ventures (CRV) has been a pioneering tech VC firm since 1970. Nearly 400 startups fueled, from Twitter to DoorDash. With over $4.3 billion in 18 funds, CRV’s rapid decisions and unwavering support make it a venture powerhouse. Innovation is their heartbeat!

Industries: Tech-focused (BIO, Consumer, Enterprise)

Funding stage: Early stage

Average check size: $10M-$20M

Number of investments: 600+

Number of exits: Undisclosed

Notable portfolio companies: Airtable, Vercel, Doordash

Contacts: LinkedIn

11. Spark Capital

➡️ Spark Capital, with 160+ bold investments in consumer, commerce, FinTech, software, and media, Spark takes risks that pay off. Operating from SF, Boston, and NYC, they’ve backed giants like Twitter and Warby Parker. No sector or stage is too early for Spark—dare to innovate with them!

Industries: Tech-focused (BIO, Consumer, Enterprise)

Funding stage: Early stage, Growth stage

Average check size: $500K-$25M

Number of exits: Undisclosed

Notable portfolio companies: Slack, Wayfair, Grammarly

Contacts: Email, LinkedIn

12. PJC

➡️ PJC, startup champs with deep industry know-how. They’ve fueled 100+ early-stage Enterprise, Consumer, and AI stars, like Expensify and Nest. One of the Boston based venture capital firms, PJC goes beyond cash—providing support, insights, and financial expertise for startup success!

Industries: AI, enterprise & consumer tech (open for investments in other verticals)

Funding stage: Early stage

Average check size: $500K-3M

Number of investments: 100+

Number of exits:  Undisclosed

Notable portfolio companies: Nest, Evergage, Expensify

Contacts: Email, LinkedIn

13. Underscore VC

➡️ Underscore VC, Boston’s startup maestro since 2015! Partners, not just investors. Think Linktree, Coda, and Project44—big hits in their portfolio. The secret sauce? Their Core Community—a squad of experts on speed dial. With 84 investments, 30 in diversity, and a new fund in the works, Underscore VC is your VIP pass to tech success.

Industries: Tech-focused mostly

Funding stage: Early stage

Average check size: $1M-$5M

Number of investments: 40+

Number of exits: Undisclosed

Notable portfolio companies: Marley, Cloudzero, Coldcast

Contacts: Email, LinkedIn

14. Summit Partners

➡️ Summit Partners, for 40 years, making big hits in tech and healthcare like Webex, Uber, and Reverb. They don’t just invest; they help firms grow big, all the way to IPOs. With 500+ investments and 200+ successful exits, Summit Partners is truly a gem.

Industries: Technology, healthcare & life science, growth products and services

Funding stage: Early stage-Growth stage

Average check size: $10M-$500M

Value-added beyond money: 

The company also offers services in product strategy, global expansion, recruitment, and preparation for IPOs and M&As.

Number of investments: 500+

Number of exits: 200+

Notable portfolio companies: Webex, Uber, Reverb

Contacts: LinkedIn, Contact page

15. Flybridge Capital Partners

➡️ Flybridge Capital Partners, pioneering AI since ’02, with $1B+ and nine network funds, are the genius behind Codecademy, BetterCloud, and FalconX. More than investors — your ultimate 360° AI success squad!

Industries: Companies built with AI

Funding stage: Early stage (Pre-seed, Seed) mostly + opportunity fund to support growth

Average check size: 

Pre-seed: $50K-$150K

Seed: $1M

Later-stage: $10M+

Value-added beyond money: 

Next Wave Funds—platform empowers pre-seed startups with up to $250K and top-tier support, featuring initiatives like XFactor Ventures and The Community VC. (More details here).

Number of investments: $500M

Number of exits: Undisclosed

Notable portfolio companies: Codecademy, Better Cloud, FalconX

Contacts: Email, LinkedIn

16. HLM Ventures

➡️ HLM Ventures has been making waves in healthcare since ’83, specializing in Early-Mid stage investing. They’ve fueled the success of 60+ healthcare companies with over 20 successful exits. HLM is the ultimate go-to in healthcare tech—small team, significant impact!

Industries: Healthcare tech-enabled services, Healthtech, Biotech

Funding stage: Early-Mid stage

Average check size: Undisclosed

Number of investments: 100+

Number of exits: 20+

Notable portfolio companies: RubiconMD, Phreesia, mPulse

Contacts: LinkedIn 

17. MassVentures

➡️ MassVentures, born in the heart of Boston, MV, is the go-to VC for startups from early stage to growth and beyond. With 200+ investments, they go beyond funding, providing the capital and expertise you need, such as strategic guidance, operational support, and a network of experts.

Industries: Deep Tech

Funding stage: Early stage-Growth and beyond

Average check size: Undisclosed

Number of investments: 200+

Number of exits: Undisclosed

Notable portfolio companies: Aclarity, Inkbit, Unstack

Contacts: Contact us

18. SV Health Investors

➡️ SV Health Investors, with $1.5B in funds, are game-changers in biotech, MedTech among private equity firms in Boston. From Boston to London, SV Health drives innovation with a 20-year track record, 75 IPOs/M&As, and a mission to improve lives—one investment at a time.

Industries: Biotech, Healthtech, MedTech

Funding stage: All

Average check size: Undisclosed

Number of investments: 100+

Number of exits: 70+

Notable portfolio companies: Centauri, Spectrum, Nimbus

Contacts: Contact us

19. Mendoza Ventures

➡️ Mendoza Ventures, a dynamic VC in Boston and San Francisco, drives early-growth FintTech, AI, and Cybersecurity companies. Founded by power couple Adrian and Senofer Mendoza, they’ve made 14 investments with two exits and are gearing up for their third fund. With Listo, Finch, and Canvas in their portfolio, MV—is your Series A to C launchpad.

Industries: Fintech, AI, and Cybersecurity

Funding stage: Early stage-Growth

Average check size: Undisclosed

Number of investments: 14

Number of exits: 2

Notable portfolio companies: Listo, FInch, Canvas

Contacts: Contact us

20. G20 Ventures

➡️ G20 Ventures, Boston’s early-stage pros since 2013! Experts in enterprise software, Web3, cryptocurrency, NFT, and DAO sectors. With 40+ investments, they’re not just financial partners but your strategic ally for success.

Industries: Software, Enterprise Software, SaaS, Internet, Information Technology

Funding stage: Early stage, Seed

Average check size: Undisclosed

Number of investments: 40+

Number of exits:

Notable portfolio companies: Fetcher, Mulberry, Narrative

Contacts: Email, LinkedIn

What’s next

Boston is a top spot for fast-growing startup investments in the U.S. in 2024. Funding is expected to rise, regular investors will keep leading, and new types of investors will join in, too. It’s the perfect time to gear up for securing funding.

If you are preparing for your investor hunt, check out our pitch deck design services to catch the right investors in Boston, create a strong story, and nail your next funding round.

Related read: Top 30 VC Firms in US in 2024

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Anastasiia

CONTENT WRITER

Hey there! I'm Anastasiia, a Content Writer at Waveup. With my marketing expertise and storytelling magic, I turn complex data and industry insights into your startup playbook, making the business world a breeze for you! At Waveup, I work with brilliant folks who make insights a never-ending flow. So, join, read, and enjoy!